What is n-propanol?
n-propanol also called n-propyl alcohol or 1-propanol or propan-1-ol is the primary alcohol with the chemical formula C3H8O. It is used widely in organic synthesis and solvents in the pharmaceutical and chemical industries. n-propanol is a colurless liquid that is completely miscible in water, ethanol, and ether. 1-propanol is one of the two isomers of propanol with the chemical formula written as CH3CH2CH2OH. The other isomer of propanol is isopropanol or isopropyl alcohol. Oxidation of n-propyl alcohol with acidic dichromate gives propionaldehyde.
The chemical formula of propanol is written as C3H8O. Therefore, the structure of propanol (n-propanol and isopropanol) contains a three-carbon chain. The chemical formula of n-propanol is written as CH3CH2CH2OH. Therefore, the hydroxyl group of n-propyl alcohol is directly bonded to the primary carbon atom of the carbon chain.
- N-propyl alcohol or propan-1-ol or n-propanol was originally obtained from fusel oil. Now, a large amount of n-propyl alcohol can be produced by the catalytic hydrogenation of propionaldehyde. Propionaldehyde can be produced by hydroformylation of ethylene by carbon monoxide and hydrogen in the presence of cobalt octacarbonyl.
H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH
- A more recent production process of n-propyl alcohol is the catalytic reduction of propargyl alcohol. Propargyl alcohol has obtained the addition of acetylene and formaldehyde in presence of a copper catalyst.
CH≡CCH2OH + 2 H2 → 2 CH3CH2CH2OH
- Naturally, 1-propanol is formed during many fermentation processes.
N-propyl alcohol is a colorless liquid with the smell of alcohol. It is miscible in water, ethanol, and ether. It is one of the two isomers of propanol. Some common properties of n-propanol are given below the table,
|Other names||n-Propyl alcohol
|Molar mass||60.096 g/mol|
|Appearance||Colorless liquid with the smell of alcohol|
|Melting point||-126 °C|
|Boiling point||97.4 °C|
|Solubility||Completely miscible in water, ethanol, and ether|
|Dipole moment||1.68 D|
It can participate in normal reactions of primary alcohol.
- Therefore, it can be reacted with an organic acid such as acetic acid in presence of sulfuric acid to form propyl acetate.
CH3COOH + CH3CH2CH2OH → CH3COOCH2CH2CH3 + H2O
- It can react with phosphorus halides to form propanol halide.
CH3CH2CH2OH + PCl5 → CH3CH2CH2Cl + HCl + POCl3
- Alcohol may be oxidized. The products of oxidation depend on the types of alcohol and the nature of the oxidizing agent. Therefore, propan-1-ol oxidized with Na2Cr2O7 and H2SO4 gives a 36% of propionaldehyde but it can be oxidized to propanoic acid in presence of chromic acid.
- It may be dehydrated to alkenes by concentrated sulfuric acid at about 170 °C.
What is n-propanol used for?
- Most commonly n-propanol uses as a solvent for waxes, vegetable oils, inks, natural resins, synthetic resins, etc.
- 1-propanol can be involved in the synthesis of many organic compounds and intermediates to produce esters, halides, propyl amines, and propyl acetate.
- N-propyl alcohol may be used as a solvent for pharmaceutical products, polishing compositions, brake fluids, lacquers, printing inks, natural gums, pigments, dye solutions, antifreeze, and de-greasing fluids.
- We used n-propanol for the production of various daily-used chemical products such as cosmetics, cleaning products, perfumes, fragrances, printing, coatings, etc.
- It is also used as a fuel additive for engines due to its high octane number. But due to its expensive nature and low energy gaining, n-propanol or n-propyl alcohol does not uses in motor fuel.